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The majority of the bioinformatics analyses that we perform for
biotech companies are confidential. However, some of that work results
in patent filings, which in time are published.
The following are two published patent applications from Corixa
Corp. that we have been involved in. All rights to these patents
are assigned to Corixa.
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Compositions
and methods for the therapy and diagnosis of ovarian cancer
WIPO Pub Number: WO 01/92581
US Patent Application: 20020132237
PA Algate, R Jones and SL
Harlocker
Compositions
and methods for the therapy and diagnosis of cancer, particularly
ovarian cancer, are disclosed. Illustrative compositions comprise
one or more ovarian tumor polypeptides, immunogenic portions
thereof, polynucleotides that encode such polypeptides, antigen
presenting cell that expresses such polypeptides, and T cells
that are specific for cells expressing such polypeptides.
The disclosed compositions are useful, for example, in the
diagnosis, prevention and/or treatment of diseases, particularly
ovarian cancer.
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Compositions
and methods for the therapy and diagnosis of acne vulgaris
WIPO Pub Number: WO 03/033515
JL Mitcham, YAW Skeiky, DH Persing, A Bhatia,
J-FL Maisonneuve, Y Zhang, S Wang, S Jen, MJ Lodes, DR Benson,
R Jones, D Carter, B Barth, J Vallieve-Douglas
Compositions and methods for the therapy and
diagnosis of acne vulgaris and other related conditions are
disclosed. Compositions may comprise one or more Propionibacterium
acnes proteins, immunogenic portions thereof, or polynucleotides
that encode such portions. Alternatively, a therapeutic composition
may comprise an antibody that binds a Propionibacterium acnes
protein, antigen presenting cell that expresses a Propionibacterium
acnes protein, or a T cell that is specific for cells expressing
such a protein. Such compositions may be used, for example,
for the prevention and/or treatment of acne.
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